LC and LC-MS Study on Establishment of Degradation Pathway of Glipizide Under Forced Decomposition Conditions
نویسندگان
چکیده
منابع مشابه
LC and LC-MS study on establishment of degradation pathway of glipizide under forced decomposition conditions.
Forced degradation studies on glipizide are conducted under the conditions of hydrolysis, oxidation, photolysis, and dry heat. The solutions are subjected to liquid chromatographic (LC) investigations to establish the number of products formed in each condition. The degradation products are characterized through isolation and subsequent NMR, IR, and MS spectral analyses, or through LC-mass spec...
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ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2008
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chromsci/46.6.510